RETOCOLITE ULCERATIVA DIAGNOSTICADA NA INFÂNCIA COM PROGRESSÃO PARA COLITE EXTENSA: RELATO DE CASO

RETOCOLITE ULCERATIVA DIAGNOSTICADA NA INFÂNCIA

Authors

  • Murilo Oliveira de carvalho Universidade do Extremo Sul Catarinense (UNESC)
  • Nicole Bento de Oliveira Universidade do extremo sul catarinense (UNESC)
  • Mauricio Oliveira de Carvalho Universidade do Extremo Sul Catarinense (UNESC)
  • Gustavo Zanette Fernandes Universidade do Extremo Sul Catarinense (UNESC)
  • Marcos Augusto Darella Lorenzin Fernandes Universidade do Extremo Sul Catarinense (UNESC)
  • Eduardo Daminelli Dalló Médico Gastroenterologista pediátrico

DOI:

https://doi.org/10.18616/inova.v13i3.8321

Abstract

Ulcerative colitis (UC) is defined by inflammation of the mucosa and submucosa of the colon and rectum1. In children, UC is rare, with an incidence of between 1 and 4 cases per 100,000/year2. Typical symptoms include abdominal pain, diarrhea, hematochezia, and tenesmus1. An 11-year-old girl weighing 32kg sought medical attention due to hematochezia. Empirical treatment with metronidazole was initiated without clinical improvement after 3 days. The patient was then hospitalized for 27 days, and stool cultures revealed Entamoeba and Salmonella, with treatment according to sensitivity. The condition progressed to bloody diarrhea (BD), prompting evaluation by a pediatric gastroenterologist, who suggested a fecal calprotectin test, which yielded elevated values. Colonoscopy was performed, showing severe UC with extensive colitis (Mayo subscore 3). Treatment with mesalazine and prednisolone was initiated, with a good response and improvement in BD. The patient was discharged with a weight of 29 kg. At the first post-discharge appointment, the patient was asymptomatic and had gained 1.8 kg. After 1 year, the patient continued regular followup with a gradual reduction in corticosteroids, remained asymptomatic, and had appropriate weight gain. Currently, she is on maintenance therapy with mesalazine and remains asymptomatic. Pediatric UC is an uncommon condition that should be considered as a differential diagnosis in children with changes in stool. In the reported case, there was a delay in diagnosis due to the need for laboratory and imaging tests. However, the patient experienced clinical improvement shortly after receiving appropriate treatment

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Published

2023-12-08